Do metoclopramide and ondansetrone alter mivacurium-induced neuromuscular blockade? – a randomised trial
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چکیده
منابع مشابه
Do metoclopramide and ondansetrone alter mivacurium-induced neuromuscular blockade? - a randomised trial.
BACKGROUND We aimed to investigate the effects of metoclopramide and ondansetrone on mivacurium neuromuscular blockade. METHODS Seventy five, ASA I-II patients, aged 18-65 and scheduled for elective surgery requiring tracheal intubation were included in the study. The patients received metoclopramide 10 mg, ondansetrone 4 mg or normal saline 5 mL; group M, group O, group NS (n=25), respective...
متن کاملThe reversal of profound mivacurium-induced neuromuscular blockade.
PURPOSE Mivacurium is metabolized by plasma cholinesterase catalyzed ester hydrolysis. Acetylcholinesterase antagonists used in the reversal of muscle relaxation may also inhibit plasma cholinesterase and, therefore, delay the hydrolysis of mivacurium. The clinical interaction between acetylcholinesterase antagonists and mivacurium induced neuromuscular blockade was studied. METHOD Intraopera...
متن کاملExtended neuromuscular blockade with mivacurium following pancuronium.
A 21-year-old female weighing 55 kg was anaesthetized for facial reconstruction. After an initial bolus of pancuronium 5 mg and top-up doses of 2 mg at 135 min and 1 mg at 290 min and 335 min, no further relaxant was given for 130 min at which time neuromuscular transmission appeared fully recovered with a full train-of-four twitches and a sustained response to 50 Hz stimulation of the posterio...
متن کاملMivacurium-induced prolonged neuromuscular block.
We report a case of prolonged neuromuscular block after administration of mivacurium 0.2 mg kg-1 to a 16-yr-old patient where the duration of block was 2.5 h. The interesting points in this case were that the patient had homozygous atypical plasma cholinesterase deficiency (both parents had a normal phenotype) following liver transplantation. Investigations showed low plasma cholinesterase acti...
متن کاملChronic carbamazepine therapy does not influence mivacurium-induced neuromuscular block.
Patients receiving anticonvulsant drugs chronically are relatively resistant to some non-depolarizing neuromuscular blocking drugs. We investigated the influence of chronic carbamazepine therapy on neuromuscular block induced by mivacurium in 20 otherwise healthy individuals undergoing neurosurgical operations, 10 of whom were receiving chronic treatment with carbamazepine and the other 10 serv...
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ژورنال
عنوان ژورنال: Brazilian Journal of Anesthesiology (English Edition)
سال: 2014
ISSN: 0104-0014
DOI: 10.1016/j.bjane.2013.04.008